Christina Applegate has received devastating news.

Christina Applegate recently provided a distressing update on her MS health situation, but this is by far the first time she has had to cope with a physical crisis.

The mother-of-one was diagnosed with breast cancer at the age of 36. Following a lumpectomy, she learned with much sadness that she carried the BRCA1 genetic mutation (a gene which is associated with an increased risk of both breast and ovarian cancer).

Christina, 51, made the extreme decision to have a double mastectomy. “It got going quite soon. It was one of those things that just seemed right when I woke up,” she said.